Center for Medical Ethics and Health Policy Staff Publications
Publication Date
11-1-2022
Journal
JNCI Cancer Spectrum
DOI
10.1093/jncics/pkac078
PMID
36352501
PMCID
PMC9703956
PubMedCentral® Posted Date
11-10-2022
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Male, Humans, United States, Sarcoma, Kaposi, Incidence, Acquired Immunodeficiency Syndrome, Ethnicity, Black People, Black or African American
Abstract
Despite the overall national decline in Kaposi sarcoma (KS) incidence in the United States among persons living with HIV, previous studies suggest there might be specific subgroups of the US population that are associated with higher KS incidence rates than others. Using the 2001-2018 National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program database, we assessed KS incidence trends among young men aged 20-34 years by race and ethnicity and geographic region. Statistical significance is 2-sided. The KS incidence rate increased nationally by 1.5% per year in non-Hispanic Black men, whereas the rate decreased statistically significantly by 3.5% per year in non-Hispanic White men. A statistically significant 3.3% per year increase among young non-Hispanic Black men in the South and no change among those living in non-South regions were observed. Targeted HIV prevention and treatment in young non-Hispanic Black men in the South and further research addressing the increased KS incidence and burden in this vulnerable population are needed.