Children’s Nutrition Research Center Staff Publications
Language
English
Publication Date
5-1-2024
Journal
Neurogastroenterology & Motility
DOI
10.1111/nmo.14777
PMID
38454301
PMCID
PMC11149999
PubMedCentral® Posted Date
5-1-2025
PubMedCentral® Full Text Version
Author MSS
Abstract
BACKGROUND: Avoidant/restrictive food intake disorder (ARFID) prevalence in children with gastroparesis (Gp) and/or functional dyspepsia (FD) is unknown. We aimed to identify ARFID prevalence and trajectory over 2 months in children with Gp, FD, and healthy children (HC) using two screening questionnaires. We also explored the frequency of a positive ARFID screen between those with/without delayed gastric emptying or abnormal fundic accommodation.
METHODS: In this prospective longitudinal study conducted at an urban tertiary care hospital, patients ages 10-17 years with Gp or FD and age- and gender-matched HC completed two validated ARFID screening tools at baseline and 2-month follow-up: the Nine Item ARFID Screen (NIAS) and the Pica, ARFID, and Rumination Disorder Interview-ARFID Questionnaire (PARDI-AR-Q). Gastric retention and fundic accommodation (for Gp and FD) were determined from gastric emptying scintigraphy.
KEY RESULTS: At baseline, the proportion of children screening positive for ARFID on the NIAS versus PARDI-AR-Q was Gp: 48.5% versus 63.6%, FD: 66.7% versus 65.2%, HC: 15.3% versus 9.7%, respectively; p < 0.0001 across groups. Of children who screened positive at baseline and participated in the follow-up, 71.9% and 53.3% were positive 2 months later (NIAS versus PARDI-AR-Q, respectively). A positive ARFID screen in Gp or FD was not related to the presence/absence of delayed gastric retention or abnormal fundic accommodation.
CONCLUSIONS & INFERENCES: ARFID detected from screening questionnaires is highly prevalent among children with Gp and FD and persists for at least 2 months in a substantial proportion of children. Children with these disorders should be screened for ARFID.
Keywords
Humans, Dyspepsia, Child, Gastroparesis, Female, Male, Adolescent, Prevalence, Prospective Studies, Longitudinal Studies, Avoidant Restrictive Food Intake Disorder, Gastric Emptying, Surveys and Questionnaires
Published Open-Access
yes
Recommended Citation
Kaul, Isha; Burton-Murray, Helen; Musaad, Salma; et al., "Avoidant/Restrictive Food Intake Disorder Prevalence Is High in Children With Gastroparesis and Functional Dyspepsia" (2024). Children’s Nutrition Research Center Staff Publications. 255.
https://digitalcommons.library.tmc.edu/staff_pub/255
Included in
Biochemical Phenomena, Metabolism, and Nutrition Commons, Dietetics and Clinical Nutrition Commons, Endocrinology, Diabetes, and Metabolism Commons, Nutrition Commons