Children’s Nutrition Research Center Staff Publications
Language
English
Publication Date
1-1-2022
Journal
Frontiers in Medicine
DOI
10.3389/fmed.2022.975376
PMID
36457577
PMCID
PMC9705792
PubMedCentral® Posted Date
11-15-2022
PubMedCentral® Full Text Version
Post-print
Abstract
Background and aims: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to present a bibliometric review of publications over the past 20 years and predict research hot spots.
Methods: Relevant publications between 2002 and 2021 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) of the Web of Science Core Collection (WoSCC) database on April 22, 2022. CiteSpace (version 5.8 R3c), VOSviewer, the Online Analysis Platform of Literature Metrology, and the R package bibliometrix were used to analyze and visualize.
Results: A total of 233 articles have been published between 2002 and 2021. The number of publication outputs increased rapidly since 2016. The collaboration network revealed that the USA, Baylor College of Medicine, and Vassilia Theodorou were the most influential country, institute, and scholar, respectively. Alimentary pharmacology and therapeutics and Gut were the most co-cited journal and Neurogastroenterology and Motility was the most productive journal. Visceral sensitivity, fibromyalgia, gastrointestinal, chronic pain, stress, gut microbiome, LGG, brain-gut axis, SLAB51, and sequencing were the top 10 clusters in co-occurrence cluster analysis. Keyword burst detection indicated that the brain-gut axis and short-chain fatty acid were the current research hot spots.
Conclusion: Research on the links between the gut microbiota and pain has increased rapidly since 2016. The current research focused on the brain-gut axis and short-chain fatty acid. Accordingly, the SCFAs-mediated mechanism of pain regulation will be a research direction of great importance on the links between the gut microbiota and pain. This study provided instructive assistance to direct future research efforts on the links between the gut microbiota and pain.
Keywords
gut microbiota, pain, bibliometric analysis, hot spots, CiteSpace
Published Open-Access
yes
Recommended Citation
Mao, Menghan; Zhou, Yanyu; Jiao, Yingfu; et al., "Bibliometric and Visual Analysis of Research on the Links Between the Gut Microbiota and Pain From 2002 to 2021" (2022). Children’s Nutrition Research Center Staff Publications. 288.
https://digitalcommons.library.tmc.edu/staff_pub/288
Included in
Biochemical Phenomena, Metabolism, and Nutrition Commons, Dietetics and Clinical Nutrition Commons, Endocrinology, Diabetes, and Metabolism Commons, Nutrition Commons