Children’s Nutrition Research Center Staff Publications

Publication Date

7-1-2025

Journal

Nature Metabolism

DOI

10.1038/s42255-025-01323-9

PMID

40542297

PMCID

PMC12893352

PubMedCentral® Posted Date

2-12-2026

PubMedCentral® Full Text Version

Author MSS

Abstract

Clustering and nesting (C&N) arise in many preclinical studies such as when animals are group-housed, share litters, or in cell culture. Ignoring C&N undermines the validity of analyses. We explain how C&N arise and valid designs and analyses.

Published Open-Access

yes

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