A Case of Autosomal Dominant Polycystic Kidney Disease With Multiple Bilateral Spontaneous Retroperitoneal Hemorrhages

Authors

• Masato Mizuta
• Tatsuya Suwabe
• Yuki Oba
• Akinari Sekine
• Masayuki Yamanouchi
• Hiroki Mizuno
• Eiko Hasegawa
• Takehiko Wada
• Makoto Fukuda
• Motoaki Miyazono
• Naoki Sawa
• Yoshifumi Ubara

Language

English

Publication Date

3-9-2026

Journal

CEN Case Reports

DOI

10.1007/s13730-025-01079-x

PMID

41801321

PMCID

PMC12972201

PubMedCentral® Posted Date

3-9-2026

PubMedCentral® Full Text Version

Post-print

Abstract

We experienced a 45-year-old male with ADPKD who developed spontaneous retroperitoneal hemorrhages with hypertension in the right subcapsular renal space without trauma. After his condition worsened with conservative management, he was treated by renal transarterial embolization (TAE). Over the next eight years, he experienced bilateral bleeding at three different sites and underwent repeated endovascular treatment with renal TAE to stop the bleeding. After the fourth occurrence, the patient underwent hemodialysis. Although renal cysts and urinary tract bleeding occur frequently in ADPKD, retroperitoneal hemorrhage is rare; however, TAE is both effective and a good way to preserve renal function.

Keywords

Humans, Male, Polycystic Kidney, Autosomal Dominant, Middle Aged, Retroperitoneal Space, Hemorrhage, Embolization, Therapeutic, Renal Dialysis, Hypertension, Treatment Outcome, Kidney, Tomography, X-Ray Computed, Bilateral spontaneous retroperitoneal bleeding, Autosomal polycystic kidney disease (ADPKD), Subcapsular renal hematoma, Perinephric hematoma, Transarterial embolization (TAE)

Published Open-Access

yes

Recommended Citation

Mizuta, Masato; Suwabe, Tatsuya; Oba, Yuki; et al., "A Case of Autosomal Dominant Polycystic Kidney Disease With Multiple Bilateral Spontaneous Retroperitoneal Hemorrhages" (2026). Children’s Nutrition Research Center Staff Publications. 358.
https://digitalcommons.library.tmc.edu/staff_pub/358