Summer Research Program Abstracts

Program

McGovern Medical School

Year of Class

2028

Year of Participation

11-25-2026

Faculty Mentor Name

Surya N. Mundluru

Faculty Mentor Department

Orthopedic Surgery

Keywords

Initial zones of inhibition (ZOI) were comparable across all geometries during the three weeks, with nonsignificant variations. At week 2, cavity and dimple geometries showed a 10.8% (p= 0.08) and 9.2% (p= 0.14) increase in ZOI compared to solid samples, respectively. By week 3, the cavity group’s increase dropped to 1.5%, while the dimple group maintained a 7.7% increase. Solid geometries demonstrated the highest compressive strength and stiffness. Compared to solid controls, cavity geometries exhibited a 73.0% reduction in ultimate compressive force, 46.6% reduction in stiffness, and 69.2% reduction in yield strength (p< 0.001). Dimple geometries showed moderate reductions of 23.2%, 18.0%, and 22.9%, respectively but remained within the compressive strength threshold of the ISO 5822:2002 standard for bone cement (p<0.001).

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