Publication Date
1-1-2013
Journal
The Texas Heart Journal
PMID
23466623
Publication Date(s)
2013
Language
English
PMCID
PMC3568289
PubMedCentral® Posted Date
1-1-2013
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Bone neoplasms/complications, chondrosarcoma, humerus/pathology, neoplasm invasiveness, osteosarcoma/diagnosis/pathology/therapy, positron-emission tomography, thrombosis, tomography, x-ray computed, vascular neoplasms
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Tumor thrombus arising from osteosarcoma is rare. We report the case of a 20-year-old man with proximal humerus osteosarcoma, accompanied by an extensive intravascular tumor thrombus extending into the heart. Our review of the literature found 14 previous reports on osteosarcoma with tumor thrombus. The combination of positron emission tomography and computed tomography is very useful in differentiating tumor thrombus from vascular thrombus, thereby avoiding unnecessary anticoagulation therapy. This same imaging combination can also be used to evaluate the response to treatment. Surgical resection of the tumor thrombus is highly recommended. The effect of tumor thrombus on survival is still unknown.