Language
English
Publication Date
2012
Journal
The Texas Heart Institute Journal
PMID
23304015
PMCID
PMC3528235
PubMedCentral® Posted Date
2012
PubMedCentral® Full Text Version
Post-Print
Abstract
Extreme thrombocytosis is a major risk factor for excessive bleeding and for thrombosis, either of which can complicate cardiovascular surgical and interventional procedures. Extreme thrombocytosis can also cause an unusual syndrome, erythromelalgia, that results in a type of chronic microvascular occlusive arterial disease. We present the differential diagnosis of conditions that may lead to extreme thrombocytosis, 3 cases (each of which illustrates a different potential complication), and a review of the pertinent medical literature. Correcting excessive thrombocytosis is typically not difficult, whether electively or acutely, and effective therapy usually controls thrombosis and excessive hemorrhage post-procedurally.
Keywords
Coronary thrombosis/prevention & control/surgery, erythromelalgia, hemorrhage/drug therapy, hydroxyurea/therapeutic use, myeloproliferative disorders/genetics/pathology, polycythemia vera/blood, plateletpheresis, preoperative care/methods, risk factors, thrombocythemia, essential/complications/diagnosis/etiology/genetics/metabolism/physiopathology
Published Open-Access
yes
Recommended Citation
Ethan A Natelson, "Extreme Thrombocytosis and Cardiovascular Surgery: Risks and Management" (2012). The Texas Heart Institute Journal. 351.
https://digitalcommons.library.tmc.edu/texasheartinstituejournal/351