Isolated Cardiac Paraganglioma Encasing Right Coronary Artery With Evidence of Succinyl Dehydrogenase Gene Mutation: Successful Management Using Multimodality Imaging

Authors

Naveen Garg
Shashank Pandey
Shiva Madan
Subhash Yadav
Gurango Majumdar
Neeraj Jain
Manoj Jain

Publication Date

1-1-2023

Journal

The Texas Heart Journal

DOI

10.14503/THIJ-21-7639

PMID

36745744

Publication Date(s)

January 2023

Language

English

PMCID

PMC9969784

PubMedCentral® Posted Date

2-6-2023

PubMedCentral® Full Text Version

Post-Print

Published Open-Access

yes

Keywords

Female, Humans, Adrenal Gland Neoplasms, Coronary Vessels, Heart Neoplasms, Mutation, Paraganglioma, Paraganglioma, Extra-Adrenal, Pheochromocytoma

Copyright

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

Abstract

This report involves a young woman with isolated cardiac paraganglioma that was diagnosed using 68Gallium-labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-octreotide positron emission tomographic scintigraphy. For the preoperative evaluation, multimodality imaging accurately described the anatomic location of the tumor and its relationship with the surrounding tissues. The patient underwent successful surgical resection of the tumor along with right coronary artery bypass grafting. The 2-month follow-up scintigraphy was normal. Next-generation sequencing evaluation revealed a novel germline mutation for the succinate dehydrogenase subunit B gene.