Publication Date
6-4-2021
Journal
The Texas Heart Institute Journal
DOI
10.14503/THIJ-19-7092
PMID
34086955
Publication Date(s)
June 2021
Language
English
PMCID
PMC8262828
PubMedCentral® Posted Date
6-4-2021
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Blood pressure/physiology, blood pressure determination, cardiovascular diseases/physiopathology, circadian rhythm, coronary artery disease/complications, cross-sectional studies, hypertension/complications/physiopathology, predictive value of tests, risk assessment/methods, time factors
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
A high morning surge in systolic blood pressure poses a risk in people who have cardiovascular disease. We investigated the relationship between this phenomenon and the SYNTAX score I in patients who had stable coronary artery disease.
Our single-center study included 125 consecutive patients (109 men and 16 women; mean age, 54.3 ± 9 yr) in whom coronary angiography revealed stable coronary artery disease. We calculated each patient's sleep-trough morning surge in systolic blood pressure, then calculated the SYNTAX score I.
The morning surge was significantly higher in patients whose score was >22 (mean, 22.7 ± 13.2) than in those whose score was ≤22 (mean, 12.4 ± 7.5) (P <0.001). Forward stepwise logistic regression analysis revealed that morning surge in systolic blood pressure was the only independent predictor of an intermediate-to-high score (odds ratio=1.183; 95% CI, 1.025–1.364; P=0.021).
To our knowledge, this is the first study to show an association between morning surge in systolic blood pressure and the SYNTAX score I in patients who have stable coronary artery disease.
