Language
English
Publication Date
3-1-2023
Journal
The Texas Heart Institute Journal
DOI
10.14503/THIJ-22-7884
PMID
36940421
PMCID
PMC10178651
PubMedCentral® Posted Date
3-21-2023
PubMedCentral® Full Text Version
Post-Print
Abstract
BACKGROUND: Significant uncertainty exists about the optimal timing of surgery for infectious endocarditis (IE) surgery in patients with active SARS-CoV-2 infection. This case series and a systematic review of the literature were carried out to evaluate the timing of surgery and postsurgical outcomes for patients with COVID-19-associated IE.
METHODS: The PubMed database was searched for reports published from June 20, 2020, to June 24, 2021, that contained the terms infective endocarditis and COVID-19. A case series of 8 patients from the authors' facility was also added.
RESULTS: A total of 12 cases were included, including 4 case reports that met inclusion criteria in addition to a case series of 8 patients from the authors' facility. Mean (SD) patient age was 61.9 (17.1) years, and patients were predominantly male (91.7%). Being overweight was the main comorbidity among patients studied (7/8 [87.5%]). Among all patients evaluated in this study, dyspnea (n = 8 [66.7%]) was the leading symptom, followed by fever (n = 7 [58.3%]). Enterococcus faecalis and Staphylococcus aureus caused 75.0% of COVID-19-associated IE. The mean (SD) time to surgery was 14.5 (15.6) days (median, 13 days). In-hospital and 30-day mortality for all evaluated patients was 16.7% (n = 2).
CONCLUSION: Clinicians must carefully assess patients diagnosed with COVID-19 to prevent missing underlying diseases such as IE. If IE is suspected, clinicians should avoid postponement of crucial diagnostic and treatment steps.
Keywords
Humans, Male, Middle Aged, Female, COVID-19, SARS-CoV-2, Endocarditis, Endocarditis, Bacterial, Cardiac Surgical Procedures
Published Open-Access
yes
Recommended Citation
Taghizadeh-Waghefi, Ali; Petrov, Asen; Wilbring, Manuel; et al., "Cardiac Surgery for Treatment of COVID-19-Associated Infectious Endocarditis" (2023). The Texas Heart Institute Journal. 9.
https://digitalcommons.library.tmc.edu/texasheartinstituejournal/9