Decoding Growth Hormone Actions on Human Growth Plate Stem Cells

Authors

• Shion Orikasa
• Noriaki Ono

Publication Date

6-5-2026

DOI

10.1016/j.tem.2026.05.007

PMID

42248738

PMCID

PMC13245359

PubMedCentral® Posted Date

6-9-2026

PubMedCentral® Full Text Version

Author MSS

Abstract

The epiphyseal growth plate is the key target of growth hormone (GH) therapy. Although growth plate stem cells are well defined in mice, their presence in humans was unclear. Using rare surgical specimens, the study by Chu et al. reveals conserved, GH-responsive stem cells in the human pubertal growth plate.

Published Open-Access

yes

Recommended Citation

Shion Orikasa and Noriaki Ono, "Decoding Growth Hormone Actions on Human Growth Plate Stem Cells" (2026). Faculty, Staff and Student Publications. 206.
https://digitalcommons.library.tmc.edu/uthdb_docs/206