Faculty, Staff and Student Publications
Language
English
Publication Date
5-1-2023
Journal
Brain Topography
DOI
10.1007/s10548-023-00955-y
PMID
37148369
PMCID
PMC10164017
PubMedCentral® Posted Date
April 2023
PubMedCentral® Full Text Version
Post-print
Abstract
The Papez circuit, first proposed by James Papez in 1937, is a circuit believed to control memory and emotions, composed of the cingulate cortex, entorhinal cortex, parahippocampal gyrus, hippocampus, hypothalamus, and thalamus. Pursuant to James Papez, Paul Yakovlev and Paul MacLean incorporated the prefrontal/orbitofrontal cortex, septum, amygdalae, and anterior temporal lobes into the limbic system. Over the past few years, diffusion-weighted tractography techniques revealed additional limbic fiber connectivity, which incorporates multiple circuits to the already known complex limbic network. In the current review, we aimed to comprehensively summarize the anatomy of the limbic system and elaborate on the anatomical connectivity of the limbic circuits based on the published literature as an update to the original Papez circuit.
Keywords
Humans, Limbic System, Gyrus Cinguli, Amygdala, Thalamus, Hippocampus, Neural Pathways
Published Open-Access
yes
Recommended Citation
Kamali, Arash; Milosavljevic, Sofia; Gandhi, Anusha; et al., "The Critical Role of Mentorship In Academic Career Development: A Commentary On Proposed Initiatives By The International Society For Bipolar Disorders Early Mid-Career Committee" (2023). Faculty, Staff and Student Publications. 1075.
https://digitalcommons.library.tmc.edu/uthmed_docs/1075