Faculty, Staff and Student Publications
Publication Date
1-1-2024
Journal
Radiology Case Reports
Abstract
Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes.
Keywords
Parry-Romberg syndrome, Progressive facial hemiatrophy, Neuroimaging, Brain MRI, Late-onset, Atypical manifestations
DOI
10.1016/j.radcr.2023.10.032
PMID
38046926
PMCID
PMC10692462
PubMedCentral® Posted Date
November 2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes