Vancomycin-resistant Enterococcus faecalis endocarditis: linezolid failure and strain characterization of virulence factors

Authors

Constantine Tsigrelis
Kavindra V Singh
Thais D Coutinho
Barbara E Murray
Larry M Baddour

Publication Date

2-1-2007

Journal

Journal of Clinical Microbiology

Abstract

Infective endocarditis due to vancomycin-resistant (VR) Enterococcus faecalis has only rarely been reported. We report a case of VR E. faecalis endocarditis that failed to respond to linezolid therapy, outline the virulence traits of the isolate, and review previously published cases of VR E. faecalis endocarditis.

Keywords

Acetamides, Adult, Anti-Infective Agents, Bacterial Proteins, Endocarditis, Bacterial, Enterococcus faecalis, Female, Gram-Positive Bacterial Infections, Humans, Oxazolidinones, Treatment Failure, Vancomycin Resistance, Virulence, Virulence Factors