Case Report: Successful Treatment of A Child With COVID-19 Reinfection-Induced Fulminant Myocarditis By Cytokine-Adsorbing Oxiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation

Authors

Phuc H Phan
Dung T Nguyen
Nam H Dao
Ha T T Nguyen
An V Vu
Son T Hoang
Lam V Nguyen
Tung V Cao
Dien M Tran

Language

English

Publication Date

6-12-2022

Journal

Frontiers in Pediatrics

DOI

10.3389/fped.2022.946547

PMID

35903158

PMCID

PMC9315247

PubMedCentral® Posted Date

July 2022

PubMedCentral® Full Text Version

Post-print

Abstract

BACKGROUND: Indirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of instituting veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiac compromise has been reported. However, current literature enunciates a paucity of available data on the effectiveness of these novel modalities.

CASE PRESENTATION: We reported a 9-year-old boy with recurrent COVID-19 infection-causing fulminant myocarditis, who was treated successfully by using novel modalities of

CONCLUSION: We conclude that the novel highly-absorptive hemofilter CVVH and VA-ECMO may be effective treatment modalities in managing SARS-CoV-2-induced fulminant myocarditis. Our report highlights the need for further well-designed investigations to confirm this extrapolation.

Keywords

COVID-19, fulminant myocarditis, oXiris® hemofilter, ECMO, case report

Published Open-Access

yes

Recommended Citation

Phan, Phuc H; Nguyen, Dung T; Dao, Nam H; et al., "Case Report: Successful Treatment of A Child With COVID-19 Reinfection-Induced Fulminant Myocarditis By Cytokine-Adsorbing Oxiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation" (2022). Faculty, Staff and Student Publications. 1748.
https://digitalcommons.library.tmc.edu/uthmed_docs/1748