Synthesis, Characterization, Antiglycation Evaluation, Molecular Docking, and Admet Studies of 4-Thiazolidinone Derivatives

Authors

Nam Q H Doan
Ngan T K Nguyen
Vu B Duong
Ha T T Nguyen
Long B Vong
Diem N Duong
Nguyet-Thu T Nguyen
Tuyen L T Nguyen
Tuoi T H Do
Tuyen N Truong

Publication Date

9-27-2022

Journal

ACS Omega

Abstract

Addressing the growing burden of cancer and the shortcomings of chemotherapy in cancer treatment are the current research goals. Research to overcome the limitations of curcumin and to improve its anticancer activity via its heterocycle-fused monocarbonyl analogues (MACs) has immense potential. In this study, 32 asymmetric MACs fused with 1-aryl-1

DOI

10.1021/acsomega.2c02933

PMID

36188331

PMCID

PMC9520563

PubMedCentral® Posted Date

September 2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes