Faculty, Staff and Student Publications
Language
English
Publication Date
1-1-2019
Journal
CytoJournal
DOI
10.4103/cytojournal.cytojournal_45_18
PMID
31516536
PMCID
PMC6683416
PubMedCentral® Posted Date
July 2019
PubMedCentral® Full Text Version
Post-print
Abstract
AIMS: Since the six-tier Milan salivary gland classification has been introduced, there are very limited studies in literature reporting the risk stratification of the Milan classification.
METHODS: We retrospectively classified a total of 285 salivary gland cytology cases into Milan reporting categories; there were 23 (8.1%) nondiagnostic, 48 (16.8%) nonneoplastic, 19 (6.7%) atypia of undetermined significance (AUS), 138 (48.4%) benign neoplasm, 13 (4.6%) neoplasm of uncertain malignant potential (NUMP), 8 (2.8%) suspicious for malignancy, and 36 (12.6%) malignant. Almost 110 cases (38.6%) had surgical follow-up resections.
RESULTS: The overall risk for malignancy (ROM) was 12.5% for AUS, 3.2% for benign neoplasm, 72.7% for NUMP, and 100% for the suspicious for malignancy and malignant. The ROM for nondiagnostic and nonneoplastic categories was not representative due to limited follow-up resections. The salivary cytology had sensitivity, specificity, positive predictive value, and negative predictive value of 93.0%, 100%, 100%, and 46.2% for neoplasm and 82.3%, 95.8%, 90.3%, and 92.0% for malignant.
CONCLUSION: Our study supports the adaptation of the six-tier Milan classification for reporting salivary gland cytology, as well as emphasizing the utility of the NUMP category.
Keywords
Fine-needle aspiration, Milan classification, risk for malignancy, salivary gland
Published Open-Access
yes
Recommended Citation
Liang, Christine A; Liu, Jing; Ogunniyi, Jaiyeola Thomas; et al., "The Role of Botulinum Toxin Type-A In Spasticity: Research Trends From A Bibliometric Analysis" (2019). Faculty, Staff and Student Publications. 1947.
https://digitalcommons.library.tmc.edu/uthmed_docs/1947