Yttrium-90 Selective Internal Radiotherapy As Bridge To Curative Hepatectomy For Recurrent Malignant Solid Pseudopapillary Neoplasm of Pancreas: Case Report and Review of Literature

Authors

Adam R Dyas
David Thor Johnson
Erin Rubin
Richard D Schulick
Piyush Kumar Sharma

Publication Date

9-1-2020

Journal

Journal of Surgical Case Reports

Abstract

Recurrent malignant solid pseudopapillary neoplasms of the pancreas (SPNP) are rare tumors with unpredictable clinical and histopathological features. There is a lack of consensus regarding utilization of adjuvant modalities in conjunction with or in lieu of curative metastatectomy. We present a remarkable case where Yttrium-90 selective internal radiation therapy (Y-90 SIRT) was successfully utilized to elucidate underlying tumor biology and aid resection of a large multifocal recurrent metastatic SPNP in the right hemi-liver of a 59-year-old female. Thus, in cases where curative metastatectomy remains the treatment goal in management of recurrent and/or metastatic SPNPs, Y-90 SIRT is a safe and effective adjunct treatment to facilitate curative resection.

DOI

10.1093/jscr/rjaa325

PMID

33005321

PMCID

PMC7515723

PubMedCentral® Posted Date

September 2020

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes