Rare Case of Pediatric Post-transplant Lymphoproliferative Disorder Presenting with Pleural Masses Complicated by Pleural Effusions

Authors

Erini Nessim Kostandy
David Wan
Essam Imseis

Publication Date

9-1-2023

Journal

ACG Case Reports Journal

Abstract

Post-transplant lymphoproliferative disorder is a complication in organ transplant recipients characterized by uncontrolled proliferation of B-lymphocytes, occurring in 6% of pediatric patients, with risk factors including primary Epstein-Barr virus infection, intensity of immunosuppression, and cytomegalovirus infection. The clinical symptoms are often nonspecific, and it is associated with a high mortality rate if left untreated. We describe a rare case of post-transplant lymphoproliferative disorder who presented with pleural-based masses resulting in pleural effusions.

Keywords

post transplant lymphoproliferative disorder, pediatric liver transplant, liver transplant complications, tacrolimus, pleural masses, pediatric transplant, pediatric immune suppression

Comments

PMID: 37753100