Publication Date
11-1-2021
Journal
Journal of Perinatology
Abstract
OBJECTIVE: The objective of this study was to determine whether abrupt discontinuation vs gradual wean of nasal CPAP (NCPAP) in infantstherapy.
STUDY DESIGN: We performed a single-center, randomized control trial of premature infants born(n = 66), comparing discontinuation of NCPAP from 6 cmH
RESULTS: Duration of NCPAP or mechanical ventilation was longer in the slow wean arm compared to the fast wean arm (17 vs 12 days, p = 0.03). There were no differences observed in secondary outcomes.
CONCLUSION: In weaning NCPAP, abrupt discontinuation may be associated with a shorter duration of positive pressure respiratory support compared to a gradual weaning strategy.
Keywords
Continuous Positive Airway Pressure, Feasibility Studies, Female, Gestational Age, Humans, Infant, Infant, Newborn, Infant, Premature, Pregnancy, Respiratory Distress Syndrome, Newborn, Ventilator Weaning, Risk factors, Outcomes research
Included in
Maternal and Child Health Commons, Obstetrics and Gynecology Commons, Pediatrics Commons
Comments
PMID: 34511596