Bronchiectasis Assessment In Primary Ciliary Dyskinesia: A Non-Invasive Approach Using Forced Oscillation Technique

Authors

Wilfredo De Jesús-Rojas
Luis Reyes-Peña
José Muñiz-Hernández
Patricia Quiles Ruiz de Porras
Jesús Meléndez-Montañez
Marcos J Ramos-Benitez
Ricardo A Mosquera

Publication Date

7-6-2023

Journal

Diagnostics

Abstract

Primary ciliary dyskinesia (PCD) is an autosomal recessive disorder that results from the dysfunction of motile cilia, which can cause chronic upper and lower respiratory infections leading to bronchiectasis. However, there is a need for additional tools to monitor the progression of bronchiectasis in PCD. The forced oscillation technique (FOT) is an effort-independent lung function test that can be used to evaluate respiratory mechanics. In this retrospective study, we aimed to describe the radiographic findings associated with respiratory impedance (resistance (Rrs) and reactance (Xrs)) measured by FOT in six adult PCD patients and one pediatric with the (

Keywords

forced oscillation technique, bronchiectasis, primary ciliary dyskinesia, respiratory impedance, respiratory mechanics, preliminary research

DOI

10.3390/diagnostics13132287

PMID

37443681

PMCID

PMC10340430

PubMedCentral® Posted Date

July 2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes