Publication Date
1-1-2023
Journal
Journal of Clinical and Translational Science
Abstract
Observational studies are notoriously susceptible to bias, and parallel-group randomized trials are important to identify the best overall treatment for eligible patients. Yet, such trials can be expected to be a misleading indicator of the best treatment for some subgroups or individual patients. In selected circumstances, patients can be treated in n-of-1 trials to address the inherent heterogeneity of treatment response in clinical populations. Such trials help to accomplish the ultimate goal of all biomedical research, to optimize the care of individual patients.
Keywords
Personalized medicine, precision medicine, randomized trials, n-of-1 trials
Included in
Medical Education Commons, Medical Sciences Commons, Medical Specialties Commons, Translational Medical Research Commons
Comments
PMID: 37528940