Faculty, Staff and Student Publications
Publication Date
1-1-2023
Journal
Baylor University Medical Center Proceedings
Abstract
Although thrombocytopenia is common in end-stage liver disease, severe, refractory thrombocytopenia during liver transplantation is rare, and if immune based, usually presents months or years later. This case describes an adult woman in whom preoperative evaluation had not determined an immune-related cause of thrombocytopenia. Clot strength was dramatically impaired as measured by thrombelastography during the transplant. Following a lack of response to repeat platelet transfusions, splenectomy was performed after graft reperfusion with rapid temporal restoration of clot strength. This case shows a severe manifestation of perioperative thrombocytopenia during liver transplantation and clinically guided management when measured clot strength is too low for accurate determination.
Keywords
Liver transplant, splenectomy, thrombelastography, thrombocytopenia
DOI
10.1080/08998280.2022.2126928
PMID
36578624
PMCID
PMC9762830
PubMedCentral® Posted Date
October 2022
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Hemic and Lymphatic Diseases Commons, Internal Medicine Commons, Medical Sciences Commons, Mental and Social Health Commons, Nephrology Commons, Surgery Commons