Faculty, Staff and Student Publications

Language

English

Publication Date

7-31-2024

Journal

Neurosurgical Review

DOI

10.1007/s10143-024-02527-5

PMID

39083214

PMCID

PMC11291542

PubMedCentral® Posted Date

7-31-2024

PubMedCentral® Full Text Version

Post-print

Abstract

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p <  0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.

Keywords

Humans, Intracranial Aneurysm, Male, Propensity Score, Female, Middle Aged, Retrospective Studies, Aged, Endovascular Procedures, Treatment Outcome, Adult, Embolization, Therapeutic

Published Open-Access

yes

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