Faculty, Staff and Student Publications
Language
English
Publication Date
4-26-2024
Journal
Viruses
DOI
10.3390/v16050680
PMID
38793561
PMCID
PMC11125882
PubMedCentral® Posted Date
4-26-2024
PubMedCentral® Full Text Version
Post-print
Abstract
The human papillomavirus is the most common sexually transmitted infection in the world. Most HPV infections clear spontaneously within 2 years of infection; however, persistent infection can result in a wide array of diseases, ranging from genital warts to cancer. Most cases of cervical, anal, and oropharyngeal cancers are due to HPV infection, with cervical cancer being one of the leading causes of cancer death in women worldwide. Screening is available for HPV and cervical cancer, but is not available everywhere, particularly in lower-resource settings. HPV infection disproportionally affects individuals living with HIV, resulting in decreased clearance, increased development of cancer, and increased mortality. The development of the HPV vaccine has shown a drastic decrease in HPV-related diseases. The vaccine prevents cervical cancer with near 100% efficacy, if given prior to first sexual activity. Vaccination uptake remains low worldwide due to a lack of access and limited knowledge of HPV. Increasing awareness of HPV and access to vaccination are necessary to decrease cancer and HPV-related morbidity and mortality worldwide.
Keywords
Humans, Papillomavirus Infections, Papillomavirus Vaccines, Female, Uterine Cervical Neoplasms, Papillomaviridae, Neoplasms, Vaccination, Anus Neoplasms, HIV Infections, Oropharyngeal Neoplasms, Male, Human Papillomavirus Viruses, human papillomavirus, cervical cancer, HPV vaccine, HIV
Published Open-Access
yes
Recommended Citation
Jensen, JaNiese E; Becker, Greta L; Jackson, J Brooks; et al., "Human Papillomavirus and Associated Cancers: A Review" (2024). Faculty, Staff and Student Publications. 3905.
https://digitalcommons.library.tmc.edu/uthmed_docs/3905