Pulmonary Alveolar Microlithiasis in a Middle-Aged Man Presenting With Respiratory Failure: A Case Report and Review of the Literature

Authors

• Allen C Omo-Ogboi
• Joyce Ederhion
• Asad Ur Rehman
• Olanrewaju Ogunleye
• Jaiyeola Thomas-Ogunniyi

Language

English

Publication Date

2-1-2024

Journal

Cureus

DOI

10.7759/cureus.54942

PMID

38544622

PMCID

PMC10967675

PubMedCentral® Posted Date

2-26-2024

PubMedCentral® Full Text Version

Post-print

Abstract

Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease of the lung, characterized by diffuse deposits of intra-alveolar calcium phosphate microliths. It usually affects both sexes, presenting mostly in the second and third decades. The clinical course is highly variable, ranging from being asymptomatic to respiratory failure. PAM is usually diagnosed after careful clinical, radiological, and pathological evaluation, usually when patients present for other medical purposes. Here, a case of PAM in a middle-aged man presenting with acute-on-chronic hypoxemic respiratory failure is reported, with a review of the literature.

Keywords

type ii alveolar pneumocytes, intra-alveolar calcium phosphate microliths, bilateral orthotropic lung transplant, slc34a2, pulmonary alveolar microlithiasis

Published Open-Access

yes

Recommended Citation

Omo-Ogboi, Allen C; Ederhion, Joyce; Ur Rehman, Asad; et al., "Pulmonary Alveolar Microlithiasis in a Middle-Aged Man Presenting With Respiratory Failure: A Case Report and Review of the Literature" (2024). Faculty, Staff and Student Publications. 4082.
https://digitalcommons.library.tmc.edu/uthmed_docs/4082