Vertebral Tortuosity Is Associated With Increased Rate of Cardiovascular Events in Vascular Ehlers-Danlos Syndrome

Authors

Sara B Stephens
Sherene Shalhub
Nicholas Dodd
Jesse Li
Michael Huang
Seitaro Oda
Kalyan Kancherla
Tam T Doan
Siddharth K Prakash
Justin D Weigand
Federico M Asch
Taylor Beecroft
Alana Cecchi
Teniola Shittu
Liliana Preiss
Scott A LeMaire
Richard B Devereux
Reed E Pyeritz
Kathryn W Holmes
Mary J Roman
Ronald V Lacro
Ralph V Shohet
Rajesh Krishnamurthy
Kim Eagle
Peter Byers
Dianna M Milewicz
Shaine A Morris

Publication Date

10-3-2023

Journal

Journal of the American Heart Association

Abstract

Background Arterial tortuosity is associated with adverse events in Marfan and Loeys-Dietz syndromes but remains understudied in Vascular Ehlers-Danlos syndrome. Methods and Results Subjects with a pathogenic

Keywords

Humans, Male, Middle Aged, Adult, Female, Ehlers-Danlos Syndrome, Type IV, Arteries, Aortic Dissection, Loeys-Dietz Syndrome