Faculty, Staff and Student Publications

Publication Date

4-1-2023

Journal

Journal of Hematology

Abstract

Primary lymphoma of the bone (PLB) is a rare lymphoproliferative neoplasm that can present either as solitary or multiple bone lesions. We report four patients with PLB who were successfully treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) followed by consolidative radiotherapy. All patients achieved a complete remission and had excellent long-term outcomes. PLB has a favorable response to combined modality treatment with chemoimmunotherapy and radiation. Long-term outcomes of PLB tend to be better than those of non-osseous diffuse large B-cell lymphoma.

Keywords

Chemoimmunotherapy, Primary bone lymphoma, Radiotherapy

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

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