Publication Date
1-1-2022
Journal
Frontiers in Cardiovascular Medicine
Abstract
BACKGROUND: Post-transplant malignancy (PTM) causes long-term morbidity and mortality in heart transplant (HTx) recipients. However, the detailed characteristics or predictors of PTM are not well-known. We evaluated the incidence, characteristics, long-term outcomes, and predictors of
METHODS: We retrospectively analyzed the types and characteristics of
RESULTS: Two hundred and six patients (20.8%) had
CONCLUSION: Older age, white race, and longer administration of immunosuppressive therapies were independent risk factors for PTM, which was associated with increased mortality. Further research is necessary for the prevention and early detection of PTM in HTx recipients.
Keywords
post-transplant malignancy, prognosis, heart transplant, de novo malignancies after heart transplantation, outcome