A Nomogram for Predicting Upper Urinary Tract Damage Risk in Children With Neurogenic Bladder

Authors

Qi Li
Miao Cai
Qingsong Pu
Shengde Wu
Xing Liu
Tao Lin
Dawei He
Jianguo Wen
Guanghui Wei

Publication Date

1-1-2022

Journal

Frontiers in Pediatrics

Abstract

PURPOSE: To establish a predictive model for upper urinary tract damage (UUTD) in children with neurogenic bladder (NB) and verify its efficacy.

METHODS: A retrospective study was conducted that consisted of a training cohort with 167 NB patients and a validation cohort with 100 NB children. The clinical data of the two groups were compared first, and then univariate and multivariate logistic regression analyses were performed on the training cohort to identify predictors and develop the nomogram. The accuracy and clinical usefulness of the nomogram were verified by receiver operating characteristic (ROC) curve, calibration curve and decision curve analyses.

RESULTS: There were no significant differences in other parameters between the training and validation cohorts except for age (all

CONCLUSION: This study presents an effective nomogram incorporating five clinical characteristics that can be conveniently applied to assess NB children' risk of progressing to UUTD.

Keywords

child, neurogenic bladder, upper urinary tract damage, nomogram, logistic regression

Comments

PMID: 36568416