Ontology Driven Integration Platform For Clinical and Translational Research

Authors

Parsa Mirhaji, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Min Zhu, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Mattew Vagnoni, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Elmer V. Bernstam, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Jiajie Zhang, The University of Texas Health Science Center at Houston, Houston, Texas, USA
Jack W. Smith, The University of Texas Health Science Center at Houston, Houston, Texas, USA

Publication Date

2009

Journal

BMC Bioinformatics

Abstract

Semantic Web technologies offer a promising framework for integration of disparate biomedical data. In this paper we present the semantic information integration platform under development at the Center for Clinical and Translational Sciences (CCTS) at the University of Texas Health Science Center at Houston (UTHSC-H) as part of our Clinical and Translational Science Award (CTSA) program. We utilize the Semantic Web technologies not only for integrating, repurposing and classification of multi-source clinical data, but also to construct a distributed environment for information sharing, and collaboration online. Service Oriented Architecture (SOA) is used to modularize and distribute reusable services in a dynamic and distributed environment. Components of the semantic solution and its overall architecture are described.

Comments

PMCID: PMC2646248

DOI

10.1186/1471-2105-10-S2-S2

PMID

19208190

PMCID

PMC2646248

PubMedCentral® Posted Date

February 2009

PubMedCentral® Full Text Version

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