Faculty, Staff and Student Publications

Language

English

Publication Date

6-1-2024

Journal

Proceedings of the IEEE International Conference on Healthcare Informatics

DOI

10.1109/ichi61247.2024.00102

PMID

40200994

PMCID

PMC11976530

PubMedCentral® Posted Date

4-8-2025

PubMedCentral® Full Text Version

Author MSS

Abstract

Demand for genomic research data and genetic testing results from cancer patients has grown exponentially. When a patient is diagnosed with a hereditary cancer syndrome, standard practice is for providers to encourage patients to discuss their results with their relatives and encourage those relatives to have clinical genetic testing and possibly participate in genetic research. Genomic research data and genetic testing results are being shared and connected in ways never imagined. Genomic data sharing is critical for advancing precision health and increasing diversity in global genome databases. However, these advancements often come with undesirable consequences, which call for additional privacy safeguards and research practices to protect hereditary cancer patients and their families because relatives who may have genomic information in common with the patient causing privacy risks to ripple throughout a kinship network. We propose to address this gap using an interdisciplinary approach integrating bioethical principles (autonomy, non-maleficence, beneficence, respect for persons, and equity) with data science techniques to mitigate privacy risk challenges.

Keywords

Human genome, privacy, hereditary cancer, data sharing

Published Open-Access

yes

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