Faculty, Staff and Student Publications
Publication Date
9-27-2023
Journal
Microbiology Spectrum
Abstract
Bacterial infection is the most common complication following staged post-mastectomy breast reconstruction initiated with a tissue expander (TE). to limit bacterial infection, antibiotic irrigation of the surgical site is commonly performed despite little high-quality data to support this practice. We performed a prospective randomized control trial to compare the impact of saline irrigation alone to a triple antibiotic irrigation regimen (1 g cefazolin, 80 mg gentamicin, and 50,000 units of bacitracin in 500 mL of saline) for breast implant surgery. The microbiome in breasts with cancer (
Keywords
breast microbiome, breast cancer, postantibiotic effect, human microbiome, bioinformatics, clinical trials, clinical methods, microbiome, microbiota