The Predictive Value of Coronary Microvascular Dysfunction For Left Ventricular Reverse Remodelling in Dilated Cardiomyopathy

Authors

Ao Kan
Yinping Leng
Shuhao Li
Fang Lin
Qimin Fang
Xinwei Tao
Mengyao Hu
Lianggeng Gong

Publication Date

1-1-2023

Journal

Frontiers in Cardiovascular Medicine

Abstract

AIMS: to evaluate the degree of coronary microvascular dysfunction (CMD) in dilated cardiomyopathy (DCM) patients by cardiac magnetic resonance (CMR) first-pass perfusion parameters and to examine the correlation between myocardial perfusion and left ventricle reverse remodelling (LVRR).

METHODS: In this study, 94 DCM patients and 35 healthy controls matched for age and sex were included. Myocardial perfusion parameters, including upslope, time to maximum signal intensity (Time

RESULTS: With a median follow-up period of 12 months [interquartile range (IQR), 8-13], 41 DCM patients (44%) achieved LVRR. Compared with healthy controls, DCM patients presented CMD with reduced upslope, SI

CONCLUSIONS: CMD could be found in DCM patients and was more impaired in patients with non-LVRR than LVRR patients. Time

Keywords

cardiac magnetic resonance; coronary microvascular dysfunction; dilated cardiomyopathy; left ventricular reverse remodelling; myocardial perfusion