Journal Articles

Publication Date



Frontiers in Cardiovascular Medicine


AIMS: to evaluate the degree of coronary microvascular dysfunction (CMD) in dilated cardiomyopathy (DCM) patients by cardiac magnetic resonance (CMR) first-pass perfusion parameters and to examine the correlation between myocardial perfusion and left ventricle reverse remodelling (LVRR).

METHODS: In this study, 94 DCM patients and 35 healthy controls matched for age and sex were included. Myocardial perfusion parameters, including upslope, time to maximum signal intensity (Time

RESULTS: With a median follow-up period of 12 months [interquartile range (IQR), 8-13], 41 DCM patients (44%) achieved LVRR. Compared with healthy controls, DCM patients presented CMD with reduced upslope, SI

CONCLUSIONS: CMD could be found in DCM patients and was more impaired in patients with non-LVRR than LVRR patients. Time


cardiac magnetic resonance; coronary microvascular dysfunction; dilated cardiomyopathy; left ventricular reverse remodelling; myocardial perfusion

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