Journal Articles

Publication Date



American Journal of Medical Genetics


Obstructive heart defects (OHDs) share common structural lesions in arteries and cardiac valves, accounting for ~25% of all congenital heart defects. OHDs are highly heritable, resulting from interplay among maternal exposures, genetic susceptibilities, and epigenetic phenomena. A genome-wide association study was conducted in National Birth Defects Prevention Study participants (N


Case-Control Studies, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Heart Defects, Congenital, Humans, Infant, Polymorphism, Single Nucleotide



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