Faculty, Staff and Student Publications
Publication Date
1-1-2022
Journal
Survey of Ophtalmology
Abstract
Uveal coloboma is a condition defined by missing ocular tissues and is a significant cause of childhood blindness. It occurs from a failure of the optic fissure to close during embryonic development and may lead to missing parts of the iris, ciliary body, retina, choroid, and optic nerve. Because there is no treatment for coloboma, efforts have focused on prevention. While several genetic causes of coloboma have been identified, little definitive research exists regarding the environmental causes of this condition. We review the current literature on environmental factors associated with coloboma in an effort to guide future research and preventative counseling related to this condition.
Keywords
Choroid, Coloboma, Female, Humans, Pregnancy, Retina
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Eye Diseases Commons, Ophthalmology Commons, Pharmacology, Toxicology and Environmental Health Commons, Public Health Commons