Oral Lactoferrin Administration Does Not Impact the Diversity or Composition of the infant Gut Microbiota in a Peruvian Cohort

Authors

Luis González
Jose Luis Paredes Sosa
Susan Mosquito
Yesenia Filio
Pedro E Romero
Theresa J Ochoa
Pablo Tsukayama

Publication Date

12-12-2023

Journal

Microbiology Spectrum

Abstract

Previous studies have suggested that oral lactoferrin enhances diversity in the gut microbiota in infants while inhibiting the growth of opportunistic pathogens. However, the effect of lactoferrin on infant gut microbiota over time has yet to be thoroughly studied. Our study suggests that lactoferrin oral treatment in infants aged 12-18 months does not affect gut microbiome diversity and composition over time. to our knowledge, this is the first study to report the effect of lactoferrin on infant gut microbiome composition over time and helps elucidate its impact on infant health and its therapeutic potential.

Keywords

Infant, Humans, Gastrointestinal Microbiome, Lactoferrin, Peru, Feces, Administration, Oral, RNA, Ribosomal, 16S

DOI

10.1128/spectrum.00096-23

PMID

37882571

PMCID

PMC10715004

PubMedCentral® Posted Date

December 2023

PubMedCentral® Full Text Version

Post-print

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