Recent Advances in Centrifugal Spinning and Their Applications in Tissue Engineering

Authors

Shaik Merkatur Hakim Marjuban
Musfira Rahman
Syeda Sharmin Duza
Mohammad Boshir Ahmed
Dinesh K Patel
Md Saifur Rahman
Karen Lozano

Publication Date

3-1-2023

Journal

Polymers

Abstract

Over the last decade, researchers have investigated the potential of nano and microfiber scaffolds to promote wound healing, tissue regeneration, and skin protection. The centrifugal spinning technique is favored over others due to its relatively straightforward mechanism for producing large quantities of fiber. Many polymeric materials have yet to be investigated in search of those with multifunctional properties that would make them attractive in tissue applications. This literature presents the fundamental process of fiber generation, and the effects of fabrication parameters (machine, solution) on the morphologies such as fiber diameter, distribution, alignment, porous features, and mechanical properties. Additionally, a brief discussion is presented on the underlying physics of beaded morphology and continuous fiber formation. Consequently, the study provides an overview of the current advancements in centrifugally spun polymeric fiber-based materials and their morphological features, performance, and characteristics for tissue engineering applications.

Keywords

centrifugal spinning, jet trajectory, polymer solution, nanofiber, tissue engineering