Prevalence, Incidence, and Predictors of Kaposi Sarcoma-Associated Herpesvirus Infection Among Young Men Who Have Sex With Men in the Southern United States

Authors

Maverick Salyards
Ank E Nijhawan
Jacky Kuo
Sheena M Knights
Susana Lazarte
Nazzarena Labo
Wendell Miley
Denise Whitby
Lu-Yu Hwang
Anna-William Kornberg
Kayo Fujimoto
Elizabeth Y Chiao

Language

English

Publication Date

5-15-2024

Journal

The Journal of Infectious Diseases

DOI

10.1093/infdis/jiad384

PMID

37711067

PMCID

PMC11095543

PubMedCentral® Posted Date

9-15-2023

PubMedCentral® Full Text Version

Post-print

Abstract

Kaposi sarcoma (KS) continues to cause substantial morbidity and mortality in populations at risk in the southern United States. Utilizing biospecimens from the Houston site of the Young Men's Affiliate Project, 351 men who have sex with men had blood tested for KS-associated herpesvirus (KSHV) IgG. Seroprevalence, seroconversion between time points, and demographic and clinical correlates were measured. KSHV prevalence was 36.7% and incidence was 8.9 per 100 person-years. Furthermore, prevalence and incidence were higher among Black individuals, people living with HIV, and those with a history of syphilis. Further research on KSHV risk may improve health disparities in KS diagnosis and outcomes.

Keywords

Humans, Male, Herpesvirus 8, Human, Incidence, Homosexuality, Male, Prevalence, Young Adult, Adult, Seroepidemiologic Studies, Sarcoma, Kaposi, Risk Factors, Herpesviridae Infections, Adolescent, United States, HIV Infections, Antibodies, Viral, Syphilis

Published Open-Access

yes

Recommended Citation

Salyards, Maverick; Nijhawan, Ank E; Kuo, Jacky; et al., "Prevalence, Incidence, and Predictors of Kaposi Sarcoma-Associated Herpesvirus Infection Among Young Men Who Have Sex With Men in the Southern United States" (2024). Faculty, Staff and Student Publications. 779.
https://digitalcommons.library.tmc.edu/uthsph_docs/779