Faculty, Staff and Student Publications
Publication Date
5-15-2024
Journal
The Journal of Infectious Diseases
Abstract
Kaposi sarcoma (KS) continues to cause substantial morbidity and mortality in populations at risk in the southern United States. Utilizing biospecimens from the Houston site of the Young Men's Affiliate Project, 351 men who have sex with men had blood tested for KS-associated herpesvirus (KSHV) IgG. Seroprevalence, seroconversion between time points, and demographic and clinical correlates were measured. KSHV prevalence was 36.7% and incidence was 8.9 per 100 person-years. Furthermore, prevalence and incidence were higher among Black individuals, people living with HIV, and those with a history of syphilis. Further research on KSHV risk may improve health disparities in KS diagnosis and outcomes.
Keywords
Humans, Male, Herpesvirus 8, Human, Incidence, Homosexuality, Male, Prevalence, Young Adult, Adult, Seroepidemiologic Studies, Sarcoma, Kaposi, Risk Factors, Herpesviridae Infections, Adolescent, United States, HIV Infections, Antibodies, Viral, Syphilis
DOI
10.1093/infdis/jiad384
PMID
37711067
PMCID
PMC11095543
PubMedCentral® Posted Date
9-15-2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Infectious Disease Commons, Male Urogenital Diseases Commons, Oncology Commons, Public Health Commons
