Hemoadsorption with Cytosorb as Part of a Strategy to Improve Outcomes in Patients on Extracorporeal Membrane Oxygenation

Authors

Ruzica Mrkonjic, Department of Cardiac and Transplant Surgery, University Hospital Dubrava, Zagreb, CroatiaFollow

Document Type

Brano Heart Failure Forum Proceedings Paper

Abstract

The exposure of a patient’s blood to the non-endothelialized surface of the extracorporeal membrane oxygenation (ECMO) system results in the production of pro-inflammatory and anti-inflammatory cytokines. This imbalance in pro- and anti-inflammatory cytokines leads to inflammatory response syndrome, which contributes to edema, vasoplegia, and multiple organ failure among other complications. Hemoadsorption therapy, with the use of CytoSorb^® (CytoSorbents) has emerged as a well-accepted treatment option that helps control pro-inflammatory response and improve outcomes for patients on ECMO. However, studies have shown that the potential of hemoadsorption is controversial and that it is crucial for clinicians to weigh the pros and cons of the therapy when applying the technology.

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Recommended Citation

Mrkonjic, Ruzica (2024) "Hemoadsorption with Cytosorb as Part of a Strategy to Improve Outcomes in Patients on Extracorporeal Membrane Oxygenation," The VAD Journal: Vol. 10(1) :e20241015 DOI: https://doi.org/10.58464/2378-2706.1066

Available at: https://digitalcommons.library.tmc.edu/vad/vol10/iss1/5

First Page

e20241015