Article Title
Document Type
Brano Heart Failure Forum Proceedings Paper
Abstract
Gastrointestinal bleeding remains a common complication in advanced heart failure patients following implantation of continuous-flow left ventricular assist devices. While the cause is likely multifactorial, development of arterial venous malformations in the gastrointestinal mucosa are a key factor. Inhibition of angiotensin II activity has been postulated to disrupt the signaling that promotes angiogenesis in these patients. We aim to review the theoretical basis for angiotensin receptor blockade, which has been proposed and explore the published evidence regarding this therapy and gastrointestinal bleeding in LVAD patients.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
Recommended Citation
Weeks, Phillip A.
(2020)
"Angiotensin Inhibition and Gastrointestinal Bleeding Prevention in Patients with Left Ventricular Assist Devices,"
The VAD Journal: Vol. 6(2)
:e2020623 https://doi.org/10.11589/vad/e2020623
Available at:
https://digitalcommons.library.tmc.edu/vad/vol6/iss2/3
First Page
e2020623
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Cardiology Commons, Cardiovascular System Commons, Other Pharmacy and Pharmaceutical Sciences Commons, Surgery Commons