Publication Date

4-1-2018

Journal

The Texas Heart Journal

DOI

10.14503/THIJ-15-5212

PMID

29844740

Publication Date(s)

April 2018

Language

English

PMCID

PMC5940291

PubMedCentral® Posted Date

4-7-2018

PubMedCentral® Full Text Version

Post-Print

Published Open-Access

yes

Keywords

Computed Tomography Angiography, Coronary Angiography, Coronary Artery Disease, Coronary Vessels, Disease Progression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Plaque, Atherosclerotic, Prospective Studies, Ultrasonography, Interventional

Abstract

Serial measurements of coronary plaque volume have been used to evaluate drug efficacy in atherosclerotic progression. However, the usefulness of computed tomography for this purpose is unknown. We investigated whether the change in total plaque volume on coronary computed tomographic angiography is associated with the change in segment plaque volume on intravascular ultrasound. We prospectively enrolled 11 consecutive patients (mean age, 56.3 ± 5 yr; 6 men) who were to undergo serial invasive coronary angiographic examinations with use of grayscale intravascular ultrasound and coronary computed tomography, performedvolume, nor between normalized coronary plaque volume. However, in the per-patient analysis, there were strong correlations between the imaging methods for changes in total coronary and segment coronary plaque volume (

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