Publication Date
4-1-2018
Journal
The Texas Heart Journal
DOI
10.14503/THIJ-15-5212
PMID
29844740
Publication Date(s)
April 2018
Language
English
PMCID
PMC5940291
PubMedCentral® Posted Date
4-7-2018
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Computed Tomography Angiography, Coronary Angiography, Coronary Artery Disease, Coronary Vessels, Disease Progression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Plaque, Atherosclerotic, Prospective Studies, Ultrasonography, Interventional
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Serial measurements of coronary plaque volume have been used to evaluate drug efficacy in atherosclerotic progression. However, the usefulness of computed tomography for this purpose is unknown. We investigated whether the change in total plaque volume on coronary computed tomographic angiography is associated with the change in segment plaque volume on intravascular ultrasound. We prospectively enrolled 11 consecutive patients (mean age, 56.3 ± 5 yr; 6 men) who were to undergo serial invasive coronary angiographic examinations with use of grayscale intravascular ultrasound and coronary computed tomography, performedvolume, nor between normalized coronary plaque volume. However, in the per-patient analysis, there were strong correlations between the imaging methods for changes in total coronary and segment coronary plaque volume (