Publication Date

1-1-2021

Journal

The Texas Heart Institute Journal

DOI

10.14503/THIJ-19-6981

PMID

33946111

Publication Date(s)

May 2021

Language

English

PMCID

PMC8108719

PubMedCentral® Posted Date

5-4-2021

PubMedCentral® Full Text Version

Post-Print

Published Open-Access

yes

Keywords

Adult, cardioplegic solutions/administration & dosage, coronary artery bypass, heart arrest, induced/methods, length of stay, operative time, recovery of function, retrospective studies, treatment outcome

Abstract

Del Nido cardioplegic solution (DNC), used chiefly in pediatric patients, rapidly induces prolonged cardiac arrest during cardiac surgery. To determine whether surgical outcomes after coronary artery bypass grafting in a United States military veteran population differed when DNC was used instead of our standard Plegisol cardioplegia, we retrospectively reviewed 155 consecutive operations performed from July 2016 through June 2017. Del Nido cardioplegia was used to induce cardiac arrest in 70 patients, and Plegisol in 85. Compared with the Plegisol group, the DNC group had a shorter mean cardiopulmonary bypass time (96.8 vs 117 min; P48 hours, atrial fibrillation, tracheostomy, reintubation, and mechanical circulatory support. We conclude that single-dose DNC is safe, effective, and cost-effective for achieving cardiac arrest in U.S. veteran populations.

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