Publication Date
1-1-2021
Journal
The Texas Heart Institute Journal
DOI
10.14503/THIJ-19-6981
PMID
33946111
Publication Date(s)
May 2021
Language
English
PMCID
PMC8108719
PubMedCentral® Posted Date
5-4-2021
PubMedCentral® Full Text Version
Post-Print
Published Open-Access
yes
Keywords
Adult, cardioplegic solutions/administration & dosage, coronary artery bypass, heart arrest, induced/methods, length of stay, operative time, recovery of function, retrospective studies, treatment outcome
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Abstract
Del Nido cardioplegic solution (DNC), used chiefly in pediatric patients, rapidly induces prolonged cardiac arrest during cardiac surgery. To determine whether surgical outcomes after coronary artery bypass grafting in a United States military veteran population differed when DNC was used instead of our standard Plegisol cardioplegia, we retrospectively reviewed 155 consecutive operations performed from July 2016 through June 2017. Del Nido cardioplegia was used to induce cardiac arrest in 70 patients, and Plegisol in 85. Compared with the Plegisol group, the DNC group had a shorter mean cardiopulmonary bypass time (96.8 vs 117 min; P48 hours, atrial fibrillation, tracheostomy, reintubation, and mechanical circulatory support. We conclude that single-dose DNC is safe, effective, and cost-effective for achieving cardiac arrest in U.S. veteran populations.