Hyperoxidized PRDX3 as a Specific Ferroptosis Marker

Authors

Yuelong Yan
Boyi Gan

Publication Date

12-1-2023

Journal

Life Metabolism

Abstract

The lack of a reliable and specific marker for ferroptosis has hindered the advancement of treatments related to this cell death mechanism toward clinical application. A recent study published in Molecular Cell has identified hyperoxidized peroxiredoxin 3 (PRDX3) as a promising marker for ferroptosis, opening up new avenues for monitoring and targeting ferroptosis in disease treatment.

Keywords

Ferroptosis, biomarker, PRDX3, hyperoxidation, lipid peroxidation

Comments

PMID: 38179338