Language

English

Publication Date

2-29-2024

Journal

Morbidity and Mortality Weekly Report

DOI

10.15585/mmwr.mm7308a3

PMID

38421935

PMCID

PMC10907036

PubMedCentral® Posted Date

2-29-2024

PubMedCentral® Full Text Version

Post-print

Abstract

In the United States, annual influenza vaccination is recommended for all persons aged ≥6 months. Using data from four vaccine effectiveness (VE) networks during the 2023-24 influenza season, interim influenza VE was estimated among patients aged ≥6 months with acute respiratory illness-associated medical encounters using a test-negative case-control study design. Among children and adolescents aged 6 months-17 years, VE against influenza-associated outpatient visits ranged from 59% to 67% and against influenza-associated hospitalization ranged from 52% to 61%. Among adults aged ≥18 years, VE against influenza-associated outpatient visits ranged from 33% to 49% and against hospitalization from 41% to 44%. VE against influenza A ranged from 46% to 59% for children and adolescents and from 27% to 46% for adults across settings. VE against influenza B ranged from 64% to 89% for pediatric patients in outpatient settings and from 60% to 78% for all adults across settings. These findings demonstrate that the 2023-24 seasonal influenza vaccine is effective at reducing the risk for medically attended influenza virus infection. CDC recommends that all persons aged ≥6 months who have not yet been vaccinated this season get vaccinated while influenza circulates locally.

Keywords

Adolescent, Adult, Humans, Child, Influenza Vaccines, Influenza, Human, Seasons, Case-Control Studies, Vaccine Efficacy

Published Open-Access

yes

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