Language
English
Publication Date
2-1-2024
Journal
Hepatology
DOI
10.1097/HEP.0000000000000679
PMID
37943874
PMCID
PMC10872651
PubMedCentral® Posted Date
2-1-2025
PubMedCentral® Full Text Version
Author MSS
Abstract
Chronic liver disease is a significant global health problem. Epidemiological trends do not show improvement in chronic liver disease incidence but rather a shift in etiologies, with steatotic liver disease (SLD) from metabolic dysfunction and alcohol becoming increasingly important causes. Consequently, there is a pressing need to develop a comprehensive public health approach for SLD. To that end, we propose a public health framework for preventing and controlling SLD. The framework is anchored on evidence linking physical inactivity, unhealthy dietary patterns, alcohol use, and obesity with both incidence and progression of SLD. Guided by the framework, we review examples of federal/state-level, community-level, and individual-level interventions with the potential to address these determinants of SLD. Ultimately, mitigating SLD's burden requires primary risk factor reduction at multiple socioecological levels, by scaling up the World Health Organization's "best buys," in addition to developing and implementing SLD-specific control interventions.
Keywords
Humans, Public Health, Liver Diseases, Risk Factors, Alcohol Drinking, Obesity, Fatty Liver, Global Health
Published Open-Access
yes
Recommended Citation
Maya Balakrishnan and Jürgen Rehm, "A Public Health Perspective on Mitigating the Global Burden of Chronic Liver Disease" (2024). Faculty and Staff Publications. 4426.
https://digitalcommons.library.tmc.edu/baylor_docs/4426